Feb. 12, 2019—Smoking raises the risk that African Americans will wind up with peripheral artery disease (PAD), a new study cautions.
PAD develops when arteries become clogged with fatty deposits of plaque. It can lead to stroke, kidney failure, erectile dysfunction, pain when walking and even the loss of limbs.
As many as 12 million people in the U.S. have it, especially those 50 and older. But it affects African Americans disproportionately. By some estimates, PAD is almost three times more common in African Americans than Caucasians.
Smoking is a known risk factor for PAD. But until now, little was known about its impact on PAD in African Americans specifically.
Risk jumps with heavy smoking
Researchers looked at the medical records of about 5,250 adults in the Jackson Heart Study. That's a large-scale investigation of cardiovascular disease in African Americans.
They found that compared to non-smokers, current smokers were:
- Twice as likely to have beginning signs of PAD in their legs.
- Eight times as likely to have high calcium build-up in the aorta, the body's main artery.
The study also revealed a strong tie between the risk of PAD and the number of cigarettes smoked. Those who smoked 20 or more cigarettes a day had much higher odds of PAD than those who didn't light up as much.